High-Risk Cytogenetics in MM: Choosing the Best Treatment Regimen Ep 3

Episode 3 March 16, 2022 00:19:56
High-Risk Cytogenetics in MM: Choosing the Best Treatment Regimen Ep 3
COR2ED Medical Education
High-Risk Cytogenetics in MM: Choosing the Best Treatment Regimen Ep 3

Mar 16 2022 | 00:19:56

/

Show Notes

COR2ED Medical Education: In this podcast episode, myeloma experts Dr. María Victoria Mateos (Haematologist at the University Hospital Salamanca, Spain) and Dr. Alexander Lesokhin (Associate Attending on the Myeloma Service at the Memorial Sloan Kettering Cancer Center, New York, NY, USA) discuss how they choose the best treatment regimen for patients with multiple myeloma and a high-risk cytogenetic profile. 

Firstly, they discuss the treatment options available for patients with high-risk cytogenetics in the US and in Europe. However, the key question is how to decide, for each individual, which treatment option is the best one. Dr. Mateos and Dr. Lesokhin discuss the factors they consider in these decisions in their clinical practice. Although the prior treatment is the most important consideration in the relapsed setting, the type of cytogenetic abnormality also plays a role. The experts specifically discuss treatment decisions in patients with extramedullary multiple myeloma: a difficult-to-treat population.

The speakers also discuss the future of myeloma treatment. How should trial design be adapted to better meet the needs of patients with a high-risk cytogenetic profile? What will be the role of CAR-T and bispecific antibodies in this population?

The experts conclude by summarising their key take-aways from the discussion.

Other Episodes

Episode 3

October 05, 2021 00:20:25
Episode Cover

ASBMR 2021 Rare Bone Disease Highlights: Episode Three

We have partnered with international experts to provide rare bone diseases highlights from ASBMR 2021.  This is the third episode in a series of...

Listen

Episode 1

November 25, 2022 00:22:02
Episode Cover

Why iron matters in women with bleeding disorders

COR2ED Medical Education: In this podcast, Haematologists Dr Michelle Lavin and Dr Roseline d’Oiron discuss the importance of recognising and correcting iron deficiency in...

Listen

Episode 2

October 21, 2021 00:24:56
Episode Cover

Choosing the Best Treatment Regimen in Multiple Myeloma: Episode 2 – the Relapsed/Refractory Setting

In this medical education podcast series, myeloma experts Dr. Karthik Ramasamy (Haematologist and Associate Professor of Haematology at the Oxford University Hospitals in London,...

Listen