Radiopharmaceuticals in prostate cancer - radium-223 episode 1

Episode 01 May 12, 2021 00:30:53
Radiopharmaceuticals in prostate cancer - radium-223 episode 1
COR2ED Medical Education
Radiopharmaceuticals in prostate cancer - radium-223 episode 1

May 12 2021 | 00:30:53

/

Show Notes

Dr. Tanya Dorff (City of Hope Comprehensive Cancer Center, Los Angeles, USA) and Dr. Phillip Koo (Banner MD Anderson Cancer Center, Arizona, USA) discuss the latest developments in the field of radiopharmaceuticals and their use in Prostate Cancer. They are also joined by guest speaker Dr. Neal Shore (Carolina Urologic Research Center, North Carolina, USA).

In this first episode, the experts focus on the alpha emitter, Radium-223 which received regulatory approval on the basis of the phase 3 ALSYMPCA trial in patients with metastatic castration resistant prostate cancer (mCRPC) and symptomatic bone metastases. They consider mechanism of action and discuss key results from the trial and the safety profile.

The experts also review the ERA-223 and PEACE-III randomised trials which investigated the use of Radium-223 in combination with next generation androgen receptor inhibitors (ARIs). A number of real-world evidence studies are also reviewed as the experts consider where radium-223 fits into the overall treatment sequence for mCRPC patients. Radiation safety and general considerations for delivering therapy with radiopharmaceuticals are also discussed.

Other Episodes

Episode 2

February 15, 2023 00:19:43
Episode Cover

PARPi and NHA combination therapy for patients with mCRPC – a US and EU perspective

COR2ED Medical Education: Dr Neal Shore, Uro-Oncologist and Chief Medical Officer for Genesis Care and Urology and Surgical Oncology in the United States and...

Listen

Episode 2

September 27, 2022 00:21:28
Episode Cover

GI CONNECT Update from ESMO 2022 Ep 2: upper GI cancer highlights

 COR2ED Medical Education: This second GI CONNECT podcast episode, covers the highlights on gastroesophageal cancer from ESMO 2022.  Dr Sam Klempner (Massachusetts General Hospital,...

Listen

Episode 1

September 20, 2022 00:23:43
Episode Cover

GI CONNECT Update from ESMO 2022 Ep 1: lower GI cancer highlights

COR2ED Medical Education: In the first episode of this GI CONNECT podcast covering the lower gastrointestinal (GI) cancer highlights from ESMO 2022, Dr Jenny...

Listen