The role of VEGFR-TKIs in the treatment of advanced RCC alone or in combination

Episode 1 November 30, 2021 00:20:49
The role of VEGFR-TKIs in the treatment of advanced RCC alone or in combination
COR2ED Medical Education
The role of VEGFR-TKIs in the treatment of advanced RCC alone or in combination

Nov 30 2021 | 00:20:49

/

Show Notes

Prof. Thomas Powles, a Medical Oncologist from Barts Cancer Centre in the UK and Prof. Georg Hutterer, a Urologist from the Medical University of Graz, Austria, discuss the role of VEGFR-TKIs in the treatment of advanced renal cell carcinoma (RCC) alone or in combination with immunotherapy.

In this podcast, by COR2ED Medical Education, the two experts discuss key trials (CHECKMATE 214, KEYNOTE 426, CHECKMATE 9ER and CLEAR) which have led to recent updates to the ESMO and EAU treatment guidelines for RCC. Combination treatment with either VEGFR targeted therapy plus a PD-1 or CTLA-4 inhibitor in the first-line setting is discussed as well as VEGFR-TKI monotherapy options at the time of disease progression.

They also focus on how to manage treatment toxicity whilst trying to optimise treatment outcomes and preserving patients’ quality of life as well as the use of biomarkers and risk stratification models.

Other Episodes

Episode 4

October 19, 2021 00:30:42
Episode Cover

The use of VEGFR-TKIs monotherapy in the treatment of unresectable or advanced HCC in 1L setting

The use of VEGFR-TKIs monotherapy in the treatment of unresectable or advanced HCC in 1L setting: Who can benefit and guidance on implementation of...

Listen

Episode 14

June 28, 2023 00:30:45
Episode Cover

PBC Highlights from EASL 2023: Episode 1

COR2ED Medical Education: Prof. Gideon Hirschfield, Professor of Medicine, Division of Gastroenterology, University of Toronto, Canada and Dr Emma Culver, Consultant Hepatologist and Honorary...

Listen

Episode 1

November 25, 2022 00:22:02
Episode Cover

Why iron matters in women with bleeding disorders

COR2ED Medical Education: In this podcast, Haematologists Dr Michelle Lavin and Dr Roseline d’Oiron discuss the importance of recognising and correcting iron deficiency in...

Listen