GI CONNECT Update from ESMO 2022 Ep 1: lower GI cancer highlights

Episode 1 September 20, 2022 00:23:43
GI CONNECT Update from ESMO 2022 Ep 1: lower GI cancer highlights
COR2ED Medical Education
GI CONNECT Update from ESMO 2022 Ep 1: lower GI cancer highlights

Sep 20 2022 | 00:23:43

/

Show Notes

COR2ED Medical Education: In the first episode of this GI CONNECT podcast covering the lower gastrointestinal (GI) cancer highlights from ESMO 2022, Dr Jenny Seligmann, Medical Oncologist from the University of Leeds in the UK and Dr Dominik Modest, Medical Oncologist from the Charité Universitaetsmedizin, Berlin, Germany discuss a number of key oral presentations from ESMO 2022 and potential implications for clinical practice. 

They start their discussion with the  NICHE-2 which looked at neoadjuvant immune checkpoint inhibition in locally advanced MMR-deficient colon cancer. Discussion then moves to the HIPECT4 trial which explored adjuvant hyperthermic intraperitoneal chemotherapy in locally advanced colon cancer and challenges previous perceptions of HIPEC in colorectal cancer patients. The FRESCO-2 trial is reviewed which evaluated the efficacy and safety of fruquintinib in patients with refractory metastatic CRC with results potentially supporting a new option for these patients. The experts then review two trials in patients with KRASG12C mutant CRC, the KRYSTAL-1 which used adagrasib with or without cetuximab in these patients and the CodeBreaK101 study which used sotorasib in combination with panitumumab.  They discuss their opinions on the results from these studies and the implications for clinical practice.

Other Episodes

Episode 2

September 14, 2022 00:15:17
Episode Cover

ASBMR 2022 Rare Bone Disease Highlights: Episode 2

In this second episode of a three-episode podcast series, COR2ED and ASBMR have partnered with Professor Eric Rush (Children’s Mercy Hospital) to provide rare...

Listen

Episode 2

July 11, 2022 00:23:31
Episode Cover

Shared decision-making in nmCRPC

Shared decision-making in nmCRPC: Treatment considerations to maintain quality of life COR2ED Medical Education: Brenda Martone, a nurse practitioner at Northwestern Medicine in Chicago...

Listen

Episode 1

November 18, 2022 00:32:39
Episode Cover

The role of SSA at progression – to continue or not?

COR2ED Medical Education: In this podcast, Prof. Martyn Caplin and Dr Aman Chauhan discuss the role of somatostatin analogues (SSAs) at progression and whether...

Listen